Toxicity Paper

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Submitted By bogiefan54
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Toxicity Paper
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Toxicity Paper Chemicals that produce systemic toxicity do not always produce the same degree of toxicity in all organs. Instead, one or two organs are usually the target of most of the toxicity produced by the toxic chemical in question. These are the target organs for the toxicity for that chemical. The organ that is the target of toxicity most commonly involved in systemic effects is the central nervous system followed by skin, blood circulation system, liver, lungs and kidneys. Muscle and bones as well as the male and female reproductive systems often suffer debilitating impacts from many substances. Target organs can also refer to an organ is targeted to receive a therapeutic dose of irradiation. An example would be beaming gamma rays to the renal area of a kidney for the treatment of a tumor. Another example of a target organ is the thyroid gland, when the anterior pituitary gland secretes a thyroid stimulating hormone (Silbergeld, 2011). Target organ toxicity is when a toxins adverse effects or disease states manifest in specific organs in the body. The higher the cardiac output, the higher the exposure. Organs each have specialized tissues and cells with differentiated cellular processes and receptors while some toxicants and metabolites may have specific reactive pathways. As pointed out previously, toxicants do not always affect all organs to the same extent. There could be several sites of action and target organs for a particular toxicant. The same organ could be targeted by more than one toxicant. The target organ may not even be where the toxicant is stored. The degree of toxic concentrations in target organs is determined by the toxicokinetic processes (Silbergeld, 2011). One of the most important organs in the body is the liver. The liver plays a key role when it comes to detoxifying foreign substances or…...

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Toxicity Paper

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The Physiologic Effects of the Crude Concoction from Euphorbia Hirta (Tawa-Tawa) Using Staphylococcus Aureus for Anti-Bacterial Tests and Animal Inoculation Assay for Toxicity 1

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Term Paper

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