Fda Standards on Anti-Depressant

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Anti-Depressant Drugs and FDA Approval

Anti-Depressant Drugs and FDA Approval Procedure
Ashley Jensen
Pima Community College Psych 101

Abstract Antidepressant drugs fall under three main categories; MOAI’s, Tricyclic Antidepressants, and SSRI’s. Like any drug, Antidepressant drugs must get FDA approval prior to putting in on the market for society, ensuring it has no harmful effects. The Food and Drug Association has a series of trials, tests, and procedures, to ensure these drugs are safe and effective for people with severe depression.
Effects of each Type of Antidepressant Drugs
Anti-Depression drugs target the amygdala by directly by increasing the activity in the prefrontal cortex, therefore decreasing the reactivity in the amygdala. The amygdala has cortical and subcortical projection to other regions of the brain, such as the hippocampus, which is where we create and maintain memories. With the cortical projections increasing the level of activity for the amygdala, there is a possibility your brain will adapt and sustain a repetitive negative associations when approached with an emotion. Anti-Depression medicines target the amygdala because the amygdala is the integrated center for emotions and an emotional behavior. (DeRubeis, R. J., Siegle, G. J., & Hollon, S. D. 2008).
Monoamine Oxidase Inhibitors MAOI’s were the first discovered anti-depressant medicine in the 1950’s, and they were originally used to treat symptoms of tuberculosis. Monoamine Oxidase is an enzyme thats primary function is used to break down three neurotransmitters; norepinephrine, serotonin, and dopamine. These three neurotransmitters are known as the mood enhancers, and by the enzyme inhibiting these neurotransmitters, it prolongs and exerts the mood-enhancer for longer periods of time.(Ciccarelli, S., & White, J. 2013, p. 537-538). MAOI’s are divided…...

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